Description: The EZH2 WT (Wild Type) Chemiluminescent Assay Kit is designed to measure activity of the EZH2 complex (EZH2/EED/SUZ12/RbAp48/ AEBP) for screening and profiling purposes.

Description: The GCN5 Chemiluminescent Assay Kit is an enzyme-linked immunosorbent assay (ELISA) designed to screen for inhibitors of GCN5. The GCN5 Chemiluminescent Assay Kit is based on the GCN5 enzyme transferring an acetyl group from an acetyl donor (acetyl CoA) to a histone substrate. The acetylated histone is recognized by a highly specific primary antibody, followed by an HRP-labeled secondary antibody. The chemiluminescence produced by HRP can be measured using a chemiluminescence reader. _x000D_

Description: The p300 Chemiluminescent Assay Kit is an enzyme-linked immunosorbent assay (ELISA) designed to screen for inhibitors of p300 or to measure histone acetyltransferase (HAT) activity for screening and profiling applications. Histone acetyltransferase p300 (also known as KAT3B) is involved in various cellular events, and its dysfunction is linked to a number of human diseases including Parkinson's, Huntington's, and Alzheimer's diseases. The P300 Chemiluminescent Assay Kit is based on the p300 enzyme transferring an acetyl group from an acetyl donor (acetyl CoA) to a histone substrate. The acetylated histone is recognized by a highly specific primary antibody, followed by an HRP-labeled secondary antibody. The chemiluminescence produced by HRP can be measured using a chemiluminescence reader._x000D_

Description: Quantitative

Description: Quantitative

Description: Quantitative

Description: The SMYD4 Chemiluminescent Assay Kit is designed to measure SMYD4_x000D_activity for screening and profiling applications. The SMYD4 Chemiluminescent Assay Kit comes_x000D_in a convenient format, with 96-well plate precoated with a specific substrate, the antibody against_x000D_methylated lysine residue of Histone H3, a secondary HRP-labeled antibody, Sadenosylmethionine,_x000D_methyltransferase assay buffer, and purified SMYD4 enzyme for 96 enzyme_x000D_reactions. The key to the SMYD4 Chemiluminescent Activity Assay Kit is a highly specific_x000D_antibody that recognizes methylated residue of Histone H3. With this kit, only three simple steps_x000D_are required for methyltransferase detection. First, S-adenosylmethionine is incubated with a_x000D_sample containing assay buffer and methyltransferase enzyme. Next, primary antibody is added._x000D_Finally, the plate is treated with an HRP-labeled secondary antibody followed by addition of the_x000D_HRP substrate to produce chemiluminescence that can then be measured using a_x000D_chemiluminescence reader.

Description: The PRMT5 Direct Activity Chemiluminescent Assay Kit is designed to measure PRMT5_x000D_ activity for screening and profiling applications. The key to the PRMT5_x000D_ Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated R3_x000D_ residue of Histone H4. With this kit, only three simple steps on a microtiter plate are_x000D_ required for methyltransferase detection. First, S-adenosylmethionine is incubated with a_x000D_ sample containing assay buffer and methyltransferase enzyme for one hour. Next,_x000D_ primary antibody is added. Finally, the plate is treated with an HRP-labeled secondary_x000D_ antibody followed by addition of the HRP substrate to produce chemiluminescence that_x000D_ can then be measured using a chemiluminescence reader.

Description: The PRMT1 Direct Activity Chemiluminescent Assay kit is designed to measure PRMT1 activity for screening and profiling applications. The key to the PRMT1_x000D_Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated R3_x000D_residue of Histone H4. With this kit, only three simple steps are required for_x000D_methyltransferase detection. First, S-adenosylmethionine is incubated with a sample_x000D_containing assay buffer and methyltransferase enzyme. Next, primary antibody is added._x000D_Finally, the strip plates are treated with an HRP-labeled secondary antibody followed by_x000D_addition of the HRP substrate to produce chemiluminescence that can then be measured_x000D_using a chemiluminescence reader.

Description: The PRMT3 Direct Activity Chemiluminescent Assay kit is designed to measure PRMT3_x000D_activity for screening and profiling applications. The key to the PRMT3 Direct Activity Assay Kit is a highly_x000D_specific antibody that recognizes methylated substrate. With this kit, only three simple_x000D_steps on a microtiter plate are required for methyltransferase detection. First,_x000D_Sadenosylmethionine is incubated with a sample containing assay buffer and_x000D_methyltransferase enzyme for one hour. Next, primary antibody is added. Finally, the_x000D_plate is treated with an HRP-labeled secondary antibody followed by addition of the HRP_x000D_substrate to produce chemiluminescence that can then be measured using a_x000D_chemiluminescence reader.

Description: The PRMT4 Direct Activity Chemiluminescent Assay kit is designed to measure PRMT4/CARM1 activity activity for screening and profiling applications. The key to the PRMT4_x000D_Chemiluminescent Assay Kit is a highly specific antibody that recognizes methylated_x000D_PRMT4 substrate. With this kit, only three simple steps on a microtiter plate are required_x000D_for methyltransferase detection. First, S-adenosylmethionine is incubated with a sample_x000D_containing assay buffer and methyltransferase enzyme. Next, primary antibody is added._x000D_Finally, the strip plates are treated with an HRP-labeled secondary antibody followed by_x000D_addition of an HRP substrate to produce chemiluminescence that can then be measured_x000D_using a chemiluminescence reader.